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Research

June 16, 2025

MSU helps advance efforts to reduce ligament injury in dog knee replacements

Louise Henderson

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Savannah Holcombe, doctoral student and Dr. Joe Hefner pictured with their dogs.

An unexpected collaboration between forensic anthropologists and veterinarians could help reduce ligament injuries during total knee replacement (TKR) surgeries in dogs.

Dr. Joe Hefner, a forensic anthropologist, and Savannah Holcombe, a doctoral student at Michigan State University (MSU), partnered with researchers from MSU’s College of Veterinary Medicine and Cambridge Veterinary School to improve the accuracy of identifying collateral ligament attachment points in dogs. Their goal is to enhance surgical planning by providing orthopedic veterinarians with more precise imaging and anatomical reference points.

Hefner explained many TKRs in dogs are less successful due to the limited visibility of the lateral and medial collateral ligaments in pre-surgical scans.

“If a medial or lateral ligament is damaged during surgery, the dog’s mobility can be severely affected,” Hefner said. “The leg will never regain its original mechanical strength.”

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To address this is, Dr. Matthew Allen of Cambridge reached out to Hefner for his expertise in 3D digitization of bone specimens.

“The goal of this project was to create a scanning method that enables precise surgical cuts using dry bone specimens as a reference—that’s where we came in,” Hefner said.

Using the Artec Space Spider, a high-resolution 3D scanner, Holcombe created detailed 3D digital models of the femur, tibia and fibula from 12 donor dogs. The bones, which varied in size, were marked with fluorescent green dots to indicate the exact attachment points of the medial and lateral collateral ligaments.

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Holcombe performs a 3D scan of a nonhuman bone using the Artec Space Spider scanner.

“The final scan resembled high-resolution photographs, capturing every detail in full color and allowing for interactive 3D viewing,” Holcombe said. “Because the scanner records both color and surface detail, it accurately captured the fluorescent markers showing where the ligaments attach.”

Hefner and Holcombe’s background in forensic anthropology—rather than veterinary medicine—helped bring a fresh perspective to the project.

“It’s exciting to explore more anatomy-focused area of the field,” Holcombe said. “Using MRI and 3D scans for clinical purposes like reducing surgical risk is a valuable way we can contribute as anthropologists.”

Their research, titled Evaluation of Collateral Ligament Location and Risk of Injury During Total Knee Replacement in Dogs, won the Collaborative Grant Award at the Veterinary Orthopedic Society’s 52nd Annual Conference.

As the research progresses, Hefner and Holcombe hope their scans enhance surgical precision and significantly reduce the risk of ligament injury during TKRs.

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