What is the Trump administration’s new global health strategy?
In September 2025, the U.S. Department of State announced its America First Global Health Strategy, a plan that aims to make “America safer, stronger and more prosperous” by encouraging other governments to take responsibility for their citizens’ health and to promote U.S. commercial and faith-based interests. It includes the commitment to purchase and distribute the breakthrough HIV preventive drug lenacapavir for up to 2 million people — principally pregnant and breastfeeding women — in 10 countries heavily affected by HIV. However, the plan does not ensure that the most vulnerable will be able to access HIV care. It comes on top of eliminating billions of dollars of U.S. financial support to global health programs. And it undermines one of the most effective foreign assistance programs in U.S. history, the U.S. President’s Emergency Plan for AIDS Relief.
Why does protecting public health abroad matter for Americans?
In a globalized world, diseases and their social and economic impacts do not stay within national boundaries. Increased rates of untreated HIV in any part of the world increase the risk of transmission for U.S. citizens. Ensuring people living with HIV worldwide receive appropriate treatment and care advances U.S. national security, diplomatic and economic interests. Ensuring that citizens in other countries enjoy good health permits their economies to thrive and America’s in turn. A healthy world is a more prosperous, peaceful and stable world to everyone’s benefit.
What impact have the cuts to PEPFAR had globally?
Since President George W. Bush initiated the program in 2003, PEPFAR has saved an estimated 26 million lives. HIV deaths have declined by 70% since 2004, and new infections fell after the program’s inception. PEPFAR helped put the world on track to ending the HIV pandemic by promoting access to highly effective drugs, supporting community-led outreach and programs, and building health care infrastructure. On Jan. 20, 2025, President Donald Trump signed an executive order that paused funding for all foreign aid programs, including PEPFAR. It shuttered PEPFAR-supported clinics and outreach programs, halted medical and supply shipments, and prompted mass layoffs of the global HIV workforce. It also dissolved USAID, which provided essential infrastructure for PEPFAR to do its work.
The Trump administration’s foreign aid pauses disrupted access to HIV treatment for more than 20 million people worldwide and access to prevention for millions more. These actions are projected to cause 4.1 million additional deaths and 7.5 million new HIV infections by 2030.
Who is being left out under the new HIV prevention strategy?
Legal pushback in the months following the Trump administration’s dismantling of USAID allowed limited parts of PEPFAR to restart. However, access to HIV prevention was explicitly limited to pregnant and breastfeeding women. Many services for other vulnerable groups were not restarted. This new strategy excludes prevention and population-specific care for the majority of people who are vulnerable to HIV infection.
About 55% of new infections worldwide occur among “key populations,” a catchall term coined by UNAIDS and WHO. These include sex workers, people who use injectable drugs, men who have sex with men, transgender people, prisoners and the sex partners of these individuals. These groups are considered “key” because of their heightened vulnerability to HIV infection and because ending the HIV pandemic cannot be achieved without their access to prevention, testing and treatment.
Stigma and discrimination, human rights abuses, criminalization and under financing of programs specific to these people’s needs are significant barriers to their care.
Why is community-based HIV care so important?
In countries with legal and social environments that discourage vulnerable people from seeking HIV services, trusted and knowledgeable peers can be a lifeline.
PEPFAR used to fund services designed and implemented by the peers of vulnerable people. People from vulnerable communities were directly involved in ensuring their peers had access to appropriate HIV services and remained in care. They also directly shaped their countries’ national HIV plans. Rather than support trusted community-led institutions, this new strategy shifts to government-run institutions.
Many people who are vulnerable to or living with HIV view government-run medical care with profound distrust and apprehension. Some participants in my own research have told me they would rather die than seek care in a government-run facility. They recount dehumanizing experiences in these facilities, including undergoing invasive procedures without consent and being openly humiliated. Health care workers have also violated patient confidentiality by disclosing patients’ sexuality and HIV status to family members, friends, neighbors, landlords or employers.
Research and lessons learned over decades of global health work suggest that carefully tailoring prevention and care strategies to each vulnerable population and addressing their unique social, behavioral, structural and medical needs improves their effectiveness.
Responses and excerpts are from an article published in The Conversation.